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Carcinogenesis In a very life time carcinogenicity study completed in B6C3F1 mice, methylphenidate prompted a rise in hepatocellular adenomas, and in males only, a rise in hepatoblastomas in a day-to-day dose of somewhere around sixty mg/kg/day. This dose is about two occasions the MRHD of 60 mg/working day specified to youngsters on mg/m2 foundati